Multiple-Trait Mapping of Quantitative Trait Loci After Selective Genotyping Using Logistic Regression

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Multiple-trait mapping of quantitative trait loci after selective genotyping using logistic regression.

Experiments to map QTL usually measure several traits, and not uncommonly genotype only those animals that are extreme for some trait(s). Analysis of selectively genotyped, multiple-trait data presents special problems, and most simple methods lead to biased estimates of the QTL effects. The use of logistic regression to estimate QTL effects is described, where the genotype is treated as the de...

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ژورنال

عنوان ژورنال: Genetics

سال: 1999

ISSN: 1943-2631

DOI: 10.1093/genetics/151.2.885